Predict and Prevent Patient Churn: The Cloud-Native Engagement Engine Playbook
Patients with chronic conditions frequently struggle with long-term adherence to treatment plans, leading to poor health outcomes, increased hospital readmissions, and higher costs for providers. For health-tech companies, this translates directly to high user churn and difficulty proving a sustained return on investment to clients.
This playbook details how to build a Cloud-Native Predictive Engagement Engine. By leveraging a powerful combination of managed cloud services, this solution ingests patient data into a scalable data warehouse, uses machine learning to predict which patients are at risk of non-adherence, and automatically triggers personalized interventions to keep them on track. It's a scalable, high-impact architecture that minimizes infrastructure management and accelerates development.
Expected Outcomes
- Significantly reduce patient churn and improve long-term engagement rates.
- Increase patient adherence to medication and other prescribed treatment plans.
- Provide a clear, data-driven ROI to health system clients by lowering preventable readmissions.
- Develop a highly scalable and maintainable system with reduced operational overhead.
- Proactively identify and support at-risk patients before they become non-adherent.
Core Tools in This Stack

Amazon SageMaker
Visit websiteA fully managed service to build, train, and deploy machine learning (ML) models for any use case with managed infrastructure, tools, and workflows.
Key Features
- Integrated Development Environment (SageMaker Studio) with JupyterLab, RStudio, and Code Editor
- Data preparation tools like Data Wrangler for data cleaning and Feature Store for managing ML features
- Managed model training and hyperparameter tuning at any scale
- One-click deployment for real-time inference and batch predictions
- Comprehensive MLOps capabilities with SageMaker Pipelines for CI/CD
- No-code ML interface for business analysts (SageMaker Canvas)
- Access, fine-tune, and deploy foundation models for generative AI (SageMaker JumpStart)
Ideal For
Company Size: Micro, Small, Medium, Large
Industries: Technology & Software, Business & Professional Services, Retail & E-commerce, Health & Wellness, Education & Non-Profit, Creative & Media
Pricing
Model: Pay-as-you-go, Free Tier
Tier: Variable
Ease of Use
Intermediate

Google BigQuery
Visit websiteA serverless, highly scalable, and cost-effective multicloud data warehouse designed for business agility, allowing users to run analytics at petabyte-scale with zero infrastructure management.
Key Features
- Serverless Architecture
- BigQuery ML
- BigQuery Omni
- BigQuery BI Engine
- Real-time Analytics
- Connected Sheets
- Geospatial Analysis
- Built-in Security and Governance
Ideal For
Company Size: Small, Medium, Large
Industries: Technology & Software, Business & Professional Services, Retail & E-commerce, Creative & Media, Health & Wellness, Education & Non-Profit
Pricing
Model: Free Tier, On-demand (Pay-as-you-go), Flat-rate Subscription
Tier: Usage-based
Ease of Use
Moderate

Twilio
Visit websiteA customer engagement platform that provides a suite of APIs and SDKs for developers to build real-time communication features like SMS, voice, video, email, and chat into their applications.
Key Features
- Programmable APIs for SMS, Voice, Video, Email, and WhatsApp.
- Twilio Flex: A fully programmable cloud contact center platform.
- Twilio Verify: API for user verification, two-factor authentication (2FA), and fraud prevention.
- Twilio Segment: A customer data platform (CDP) to collect, unify, and activate customer data.
- Extensive developer documentation, helper libraries, and SDKs in multiple languages.
- Global network infrastructure for reliable, low-latency communication.
Ideal For
Company Size: Micro, Small, Medium, Large
Industries: Technology & Software, Business & Professional Services, Retail & E-commerce, Health & Wellness, Education & Non-Profit, Other
Pricing
Model: Pay-as-you-go, Volume Discounts, Free Trial
Tier: Usage-based
Ease of Use
For Developers
The Workflow
Integration Logic
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HealthConnect Fabric
This integration follows an event-driven, multi-cloud architecture. 1) Standardized EHR/FHIR data is ingested and stored in Google BigQuery tables. 2) A scheduled Google Cloud Function periodically queries for new or updated patient records and exports them to a designated Google Cloud Storage (GCS) bucket. 3) An event-driven process (e.g., a GCS to S3 replication job) triggers an AWS Lambda function. 4) This Lambda function initiates an Amazon SageMaker Batch Transform job, feeding the patient data into a pre-trained ML model. 5) SageMaker processes the data, generates predictions (e.g., a risk score), and saves the results to an S3 bucket. 6) A second AWS Lambda function is triggered by the new prediction results in S3. 7) This function parses the results. If a prediction meets a predefined threshold (e.g., high-risk patient), it uses the Twilio API to send an automated SMS or voice call to the patient or a care coordinator, delivering a timely and relevant message.
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